Journal of the Korean Society of Stereotactic and Functional Neurosurgery 2018;14(1):14-17.
Published online June 30, 2018.
Subthalamic Nucleus Deep Brain Stimulation Treatment for Generalized Off-Period Dystonia in Parkinson's Disease : Case Report
Seri Lee, Joopyung Kim
Department of Neurosurgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea
Currently, deep brain stimulation (DBS) is the safest and the most effective surgical treatment for Parkinson's disease (PD). However, there is no general consensus on whether subthalamic nucleus (STN) or globus pallidus internus (GPi) is the best target for PD. Generally, bilateral GPi-DBS is the preferred rational surgical strategy for dystonic symptom in PD. However our case proved that bilateral STN-DBS could significantly improve off-dystonia symptoms for PD having severe generalized off-dystonia symptoms with dopamine response. Therefore, STN-DBS can be considered as treatment for generalized off-dystonia in PD patients with levodopa response.
Key Words: Deep brain stimulation, Off-period dystonia, Subthalamic nucleus, Globus pallidus internus.

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